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Potential Use of Janus Kinase Inhibitors in the Treatment of Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease with unclear pathogenesis. One characteristic of SLE is pro-inflammatory and anti-inflammatory cytokine imbalance. Janus kinase (JAK) is an intracellular non-receptor tyrosine kinase essential for many cytokine signaling pathways. D...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084827/ https://www.ncbi.nlm.nih.gov/pubmed/37051062 http://dx.doi.org/10.2147/JIR.S397639 |