KRAS-specific antibody binds to KRAS protein inside colorectal adenocarcinoma cells and inhibits its localization to the plasma membrane

Colorectal cancer (CRC) is the third highest incidence cancer and a leading cause of cancer mortality worldwide. To date, chemotherapeutic treatment of advanced CRC that has metastasized has a dismayed success rate of less than 30%. Further, most (80%) sporadic CRCs are microsatellite-stable and are...

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Detalles Bibliográficos
Autores principales: Lam, Kuen Kuen, Low, Yee Syuen, Lo, Michelle, Wong, Michelle, Leong Tang, Choong, Tan, Emile, Chok, Aik Yong, Seow-En, Isaac, Wong, Siew Heng, Cheah, Peh Yean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084885/
https://www.ncbi.nlm.nih.gov/pubmed/37051535
http://dx.doi.org/10.3389/fonc.2023.1036871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084885/
https://www.ncbi.nlm.nih.gov/pubmed/37051535
http://dx.doi.org/10.3389/fonc.2023.1036871

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