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Peptide Variant Detection by a Living Yeast Biosensor via an Epitope-Selective Protease

We previously demonstrated that we could hijack the fungal pheromone signaling pathway to provide a living yeast biosensor where peptide biomarkers were recognized by G-protein-coupled receptors and engineered to transcribe a readout. Here, we demonstrated that the protease could be reintroduced to...

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Detalles Bibliográficos
Autores principales: Crnković, Tea, Bokor, Benjamin J., Lockwood, Mead E., Cornish, Virginia W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084949/
https://www.ncbi.nlm.nih.gov/pubmed/37849458
http://dx.doi.org/10.34133/bdr.0003