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Alleviative effects of α‐lipoic acid on muscle atrophy via the modulation of TNF‐α/JNK and PI3K/AKT pathways in high‐fat diet and streptozotocin‐induced type 2 diabetic rats

Diabetes mellitus (DM) is often accompanied by clinical complications such as sarcopenia. Previous studies have indicated that oxidative stress and insulin resistance (IR) are highly associated with the pathogenesis of diabetic myopathy. α‐lipoic acid (ALA), a potent biological antioxidant, exists a...

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Detalles Bibliográficos
Autores principales: Ko, Chih‐Yuan, Wu, Chi‐Hao, Huang, Wen‐Jian, Lo, Yangming Martin, Lin, Shih‐Xiang, Wu, James Swi‐Bea, Huang, Wen‐Chung, Shen, Szu‐Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084977/
https://www.ncbi.nlm.nih.gov/pubmed/37051351
http://dx.doi.org/10.1002/fsn3.3227