Preclinical trials in Alzheimer’s disease: Sample size and effect size for behavioural and neuropathological outcomes in 5xFAD mice

5xFAD transgenic (TG) mice are used widely in AD preclinical trials; however, data on sample sizes are largely unaddressed. We therefore performed estimates of sample sizes and effect sizes for typical behavioural and neuropathological outcome measures in TG 5xFAD mice, based upon data from single-s...

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Detalles Bibliográficos
Autores principales: Faisal, Mahvish, Aid, Jana, Nodirov, Bekzod, Lee, Benjamin, Hickey, Miriam A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085059/
https://www.ncbi.nlm.nih.gov/pubmed/37036878
http://dx.doi.org/10.1371/journal.pone.0281003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085059/
https://www.ncbi.nlm.nih.gov/pubmed/37036878
http://dx.doi.org/10.1371/journal.pone.0281003

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