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In-silico EEG biomarkers of reduced inhibition in human cortical microcircuits in depression

Reduced cortical inhibition by somatostatin-expressing (SST) interneurons has been strongly associated with treatment-resistant depression. However, due to technical limitations it is impossible to establish experimentally in humans whether the effects of reduced SST interneuron inhibition on microc...

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Detalles Bibliográficos
Autores principales: Mazza, Frank, Guet-McCreight, Alexandre, Valiante, Taufik A., Griffiths, John D., Hay, Etay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085061/
https://www.ncbi.nlm.nih.gov/pubmed/37036854
http://dx.doi.org/10.1371/journal.pcbi.1010986