A novel mouse model for an inducible gene modification in the renal thick ascending limb

The thick ascending limb (TAL) is critical for renal control of fluid and ion homeostasis. The function of the TAL depends on the activity of the bumetanide-sensitive Na(+)-K(+)-2Cl(−) cotransporter (NKCC2), which is highly abundant in the luminal membrane of TAL cells. TAL function is regulated by...

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Detalles Bibliográficos
Autores principales: Bourqui, Laurent, Winter, Denise V., Odermatt, Alex, Loffing-Cueni, Dominique, Loffing, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2023
Materias:
Innovative Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085568/
https://www.ncbi.nlm.nih.gov/pubmed/36892908
http://dx.doi.org/10.1152/ajprenal.00250.2022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085568/
https://www.ncbi.nlm.nih.gov/pubmed/36892908
http://dx.doi.org/10.1152/ajprenal.00250.2022

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