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A novel mouse model for an inducible gene modification in the renal thick ascending limb
The thick ascending limb (TAL) is critical for renal control of fluid and ion homeostasis. The function of the TAL depends on the activity of the bumetanide-sensitive Na(+)-K(+)-2Cl(−) cotransporter (NKCC2), which is highly abundant in the luminal membrane of TAL cells. TAL function is regulated by...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Physiological Society
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085568/ https://www.ncbi.nlm.nih.gov/pubmed/36892908 http://dx.doi.org/10.1152/ajprenal.00250.2022 |