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PD-L1(ATTAC) mice reveal the potential of depleting PD-L1 expressing cells in cancer therapy

Antibodies targeting the PD-1 receptor and its ligand PD-L1 have shown impressive responses in some tumors of bad prognosis. We hypothesized that, since immunosuppressive cells might present several immune checkpoints on their surface, the selective elimination of PD-L1 expressing cells could be eff...

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Detalles Bibliográficos
Autores principales: Fueyo-Marcos, Elena, Lopez-Pernas, Gema, Fustero-Torre, Coral, Antón, Marta Elena, Al-Shahrour, Fátima, Fernández-Capetillo, Oscar, Murga, Matilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085585/
https://www.ncbi.nlm.nih.gov/pubmed/36947705
http://dx.doi.org/10.18632/aging.204598