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Hsp22 pretreatment protects against LPS-induced hippocampal injury by alleviating neuroinflammation and apoptosis by regulating the NLRP3/Caspase1/IL-1β signaling pathway in mice

Neuroinflammation is an important reason for the occurrence and development of cognitive impairment. The Lentiviral vector Hsp22 was constructed for intracerebroventricular injection pretreatment, LPS was used to induce the cognitive impairment model in mice, and the Morris water maze was used to ex...

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Detalles Bibliográficos
Autores principales: Peng, Shengliang, Yu, Yun, Li, Juan, Jiang, Danling, Xu, Guohai, Wu, Lidong, Hu, Jialing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085591/
https://www.ncbi.nlm.nih.gov/pubmed/36934348
http://dx.doi.org/10.18632/aging.204586