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GALNT2 sustains glioma stem cells by promoting CD44 expression

Glioblastoma (GBM) is the most prevalent and malignant brain tumor and is highly resistant to currently available treatment. In this study, we reveal that polypeptide N-acetylgalactosaminyltransferase 5 (GALNT2) expression level was elevated in GBM, IDH1 wildtype glioma, and GBM stem cells (GSCs). G...

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Detalles Bibliográficos
Autores principales: Liu, Yingying, Chen, Peisheng, Xu, Liufei, Wang, Bo, Zhang, Shengping, Wang, Xiangpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085609/
https://www.ncbi.nlm.nih.gov/pubmed/37000153
http://dx.doi.org/10.18632/aging.204609