Knockout of AMD-associated gene POLDIP2 reduces mitochondrial superoxide in human retinal pigment epithelial cells

Genetic and epidemiologic studies have significantly advanced our understanding of the genetic factors contributing to age-related macular degeneration (AMD). In particular, recent expression quantitative trait loci (eQTL) studies have highlighted POLDIP2 as a significant gene that confers risk of d...

Descripción completa

Detalles Bibliográficos
Autores principales: Nguyen, Tu, Urrutia-Cabrera, Daniel, Wang, Luozixian, Lees, Jarmon G., Wang, Jiang-Hui, Hung, Sandy S.C., Hewitt, Alex W., Edwards, Thomas L., McLenachan, Sam, Chen, Fred K., Lim, Shiang Y., Luu, Chi D., Guymer, Robyn, Wong, Raymond C.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085620/
https://www.ncbi.nlm.nih.gov/pubmed/36795578
http://dx.doi.org/10.18632/aging.204522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085620/
https://www.ncbi.nlm.nih.gov/pubmed/36795578
http://dx.doi.org/10.18632/aging.204522

Ejemplares similares