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Knockout of AMD-associated gene POLDIP2 reduces mitochondrial superoxide in human retinal pigment epithelial cells

Genetic and epidemiologic studies have significantly advanced our understanding of the genetic factors contributing to age-related macular degeneration (AMD). In particular, recent expression quantitative trait loci (eQTL) studies have highlighted POLDIP2 as a significant gene that confers risk of d...

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Detalles Bibliográficos
Autores principales:	Nguyen, Tu, Urrutia-Cabrera, Daniel, Wang, Luozixian, Lees, Jarmon G., Wang, Jiang-Hui, Hung, Sandy S.C., Hewitt, Alex W., Edwards, Thomas L., McLenachan, Sam, Chen, Fred K., Lim, Shiang Y., Luu, Chi D., Guymer, Robyn, Wong, Raymond C.B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085620/ https://www.ncbi.nlm.nih.gov/pubmed/36795578 http://dx.doi.org/10.18632/aging.204522

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