DNA i-motif formation at neutral pH is driven by kinetic partitioning

Cytosine-rich DNA regions can form four-stranded structures based on hemi-protonated C.C(+) pairs, called i-motifs (iMs). Using CD, UV absorption, NMR spectroscopy, and DSC calorimetry, we show that model (C(n)T(3))(3)C(n) (Cn) sequences adopt iM under neutral or slightly alkaline conditions for n &...

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Detalles Bibliográficos
Autores principales: Školáková, Petra, Gajarský, Martin, Palacký, Jan, Šubert, Denis, Renčiuk, Daniel, Trantírek, Lukáš, Mergny, Jean-Louis, Vorlíčková, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085675/
https://www.ncbi.nlm.nih.gov/pubmed/36912102
http://dx.doi.org/10.1093/nar/gkad119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085675/
https://www.ncbi.nlm.nih.gov/pubmed/36912102
http://dx.doi.org/10.1093/nar/gkad119

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