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When translation elongation is impaired, the mRNA is uniformly destabilized by the RNA degradosome, while the concentration of mRNA is altered along the molecule

mRNA sits at the crossroads of transcription, translation and mRNA degradation. Many questions remain about the coupling of these three processes in Escherichia coli and, in particular, how translation may have an effect on mRNA degradation and transcription. To characterize the interplay between mR...

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Detalles Bibliográficos
Autores principales: Duviau, Marie-Pierre, Chen, Fan, Emile, Anthony, Cocaign-Bousquet, Muriel, Girbal, Laurence, Nouaille, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085687/
https://www.ncbi.nlm.nih.gov/pubmed/36840715
http://dx.doi.org/10.1093/nar/gkad104