Human and bacterial TatD enzymes exhibit apurinic/apyrimidinic (AP) endonuclease activity

TatD enzymes are evolutionarily conserved deoxyribonucleases associated with DNA repair, apoptosis, development, and parasite virulence. Three TatD paralogs exist in humans, but their nuclease functions are unknown. Here, we describe the nuclease activities of two of the three human TatD paralogs, T...

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Detalles Bibliográficos
Autores principales: Dorival, Jonathan, Eichman, Brandt F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085689/
https://www.ncbi.nlm.nih.gov/pubmed/36881763
http://dx.doi.org/10.1093/nar/gkad133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085689/
https://www.ncbi.nlm.nih.gov/pubmed/36881763
http://dx.doi.org/10.1093/nar/gkad133

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