Human senataxin is a bona fide R-loop resolving enzyme and transcription termination factor

Prolonged pausing of the transcription machinery may lead to the formation of three-stranded nucleic acid structures, called R-loops, typically resulting from the annealing of the nascent RNA with the template DNA. Unscheduled persistence of R-loops and RNA polymerases may interfere with transcripti...

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Detalles Bibliográficos
Autores principales: Hasanova, Zdenka, Klapstova, Veronika, Porrua, Odil, Stefl, Richard, Sebesta, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085699/
https://www.ncbi.nlm.nih.gov/pubmed/36864660
http://dx.doi.org/10.1093/nar/gkad092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085699/
https://www.ncbi.nlm.nih.gov/pubmed/36864660
http://dx.doi.org/10.1093/nar/gkad092

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