Assembly mechanism and cryoEM structure of RecA recombination nucleofilaments from Streptococcus pneumoniae

RecA-mediated homologous recombination (HR) is a key mechanism for genome maintenance and plasticity in bacteria. It proceeds through RecA assembly into a dynamic filament on ssDNA, the presynaptic filament, which mediates DNA homology search and ordered DNA strand exchange. Here, we combined struct...

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Detalles Bibliográficos
Autores principales: Hertzog, Maud, Perry, Thomas Noé, Dupaigne, Pauline, Serres, Sandra, Morales, Violette, Soulet, Anne-Lise, Bell, Jason C, Margeat, Emmanuel, Kowalczykowski, Stephen C, Le Cam, Eric, Fronzes, Rémi, Polard, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085707/
https://www.ncbi.nlm.nih.gov/pubmed/36806960
http://dx.doi.org/10.1093/nar/gkad080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085707/
https://www.ncbi.nlm.nih.gov/pubmed/36806960
http://dx.doi.org/10.1093/nar/gkad080

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