Versatile strategy using vaccinia virus-capping enzyme to synthesize functional 5′ cap-modified mRNAs

The potential of synthetic mRNA as a genetic carrier has increased its application in scientific fields. Because the 5′ cap regulates the stability and translational activity of mRNAs, there are concerted efforts to search for and synthesize chemically-modified 5′ caps that improve the functionality...

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Detalles Bibliográficos
Autores principales: Ohno, Hirohisa, Akamine, Sae, Mochizuki, Megumi, Hayashi, Karin, Akichika, Shinichiro, Suzuki, Tsutomu, Saito, Hirohide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085709/
https://www.ncbi.nlm.nih.gov/pubmed/36731515
http://dx.doi.org/10.1093/nar/gkad019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085709/
https://www.ncbi.nlm.nih.gov/pubmed/36731515
http://dx.doi.org/10.1093/nar/gkad019

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