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Versatile strategy using vaccinia virus-capping enzyme to synthesize functional 5′ cap-modified mRNAs
The potential of synthetic mRNA as a genetic carrier has increased its application in scientific fields. Because the 5′ cap regulates the stability and translational activity of mRNAs, there are concerted efforts to search for and synthesize chemically-modified 5′ caps that improve the functionality...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085709/ https://www.ncbi.nlm.nih.gov/pubmed/36731515 http://dx.doi.org/10.1093/nar/gkad019 |