Polymer simulations guide the detection and quantification of chromatin loop extrusion by imaging

Genome-wide chromosome conformation capture (Hi-C) has revealed the organization of chromatin into topologically associating domains (TADs) and loops, which are thought to help regulate genome functions. TADs and loops are understood as the result of DNA extrusion mediated by the cohesin complex. Ho...

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Detalles Bibliográficos
Autores principales: Sabaté, Thomas, Lelandais, Benoît, Bertrand, Edouard, Zimmer, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085712/
https://www.ncbi.nlm.nih.gov/pubmed/36840746
http://dx.doi.org/10.1093/nar/gkad034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085712/
https://www.ncbi.nlm.nih.gov/pubmed/36840746
http://dx.doi.org/10.1093/nar/gkad034

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