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Diminazene aceturate exacerbates renal fibrosis after unilateral ureteral obstruction in female mice

BACKGROUND: Diminazene aceturate (DIZE), an angiotensin-converting enzyme 2 (ACE2) activator, exerts anti-inflammatory and antifibrotic effects in a variety of human chronic diseases. However, the role of DIZE in kidney fibrosis and the underlying mechanism remain unclear. Therefore, we investigated...

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Detalles Bibliográficos
Autores principales: Kim, Yosep, Kim, Jongwan, Han, Sang Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Nephrology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085718/
https://www.ncbi.nlm.nih.gov/pubmed/37037481
http://dx.doi.org/10.23876/j.krcp.22.033