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Cinnamic acid derivatives as potential matrix metalloproteinase-9 inhibitors: molecular docking and dynamics simulations

Matrix metalloproteinase-9 (MMP-9) is a zinc and calcium-dependent proteolytic enzyme involved in extracellular matrix degradation. Overexpression of MMP-9 has been confirmed in several disorders, including cancers, Alzheimer′s disease, autoimmune diseases, cardiovascular diseases, and dental caries...

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Detalles Bibliográficos
Autores principales: Malekipour, Mohammad Hossein, Shirani, Farzaneh, Moradi, Shadi, Taherkhani, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085732/
https://www.ncbi.nlm.nih.gov/pubmed/37037467
http://dx.doi.org/10.5808/gi.22077