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Evaluation of CYP2C19-Mediated Pharmacokinetic Drug Interaction of Tegoprazan, Compared with Vonoprazan or Esomeprazole

BACKGROUND AND OBJECTIVE: CYP2C19-mediated drug interactions of acid-reducing agents are clinically important given the high possibility of concomitant administration with CYP2C19 substrates. This study aimed to evaluate the effect of tegoprazan on the pharmacokinetics (PK) of a CYP2C19 substrate, p...

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Detalles Bibliográficos
Autores principales: Yang, Eunsol, Ji, Sang Chun, Jang, In-Jin, Lee, SeungHwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085907/
https://www.ncbi.nlm.nih.gov/pubmed/36897544
http://dx.doi.org/10.1007/s40262-023-01228-4