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Total escape of SARS-CoV-2 from dual monoclonal antibody therapy in an immunocompromised patient

Monoclonal antibodies (mAbs) directed against the spike of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are effective therapeutic options to combat infections in high-risk patients. Here, we report the adaptation of SARS-CoV-2 to the mAb cocktail REGN-COV in a kidney transplant patie...

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Detalles Bibliográficos
Autores principales: Jaki, Lena, Weigang, Sebastian, Kern, Lisa, Kramme, Stefanie, Wrobel, Antoni G., Grawitz, Andrea B., Nawrath, Philipp, Martin, Stephen R., Dähne, Theo, Beer, Julius, Disch, Miriam, Kolb, Philipp, Gutbrod, Lisa, Reuter, Sandra, Warnatz, Klaus, Schwemmle, Martin, Gamblin, Steven J., Neumann-Haefelin, Elke, Schnepf, Daniel, Welte, Thomas, Kochs, Georg, Huzly, Daniela, Panning, Marcus, Fuchs, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085998/
https://www.ncbi.nlm.nih.gov/pubmed/37037847
http://dx.doi.org/10.1038/s41467-023-37591-w