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KIAA1199 deficiency enhances skeletal stem cell differentiation to osteoblasts and promotes bone regeneration

Upon transplantation, skeletal stem cells (also known as bone marrow stromal or mesenchymal stem cells) can regulate bone regeneration by producing secreted factors. Here, we identify KIAA1199 as a bone marrow stromal cell-secreted factor in vitro and in vivo. KIAA1199 plasma levels of patients posi...

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Detalles Bibliográficos
Autores principales: Chen, Li, Shi, Kaikai, Ditzel, Nicholas, Qiu, Weimin, Figeac, Florence, Nielsen, Louise Himmelstrup Dreyer, Tencerova, Michaela, Kowal, Justyna Magdalena, Ding, Ming, Andreasen, Christina Møller, Andersen, Thomas Levin, Kassem, Moustapha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086002/
https://www.ncbi.nlm.nih.gov/pubmed/37037828
http://dx.doi.org/10.1038/s41467-023-37651-1