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KIAA1199 deficiency enhances skeletal stem cell differentiation to osteoblasts and promotes bone regeneration
Upon transplantation, skeletal stem cells (also known as bone marrow stromal or mesenchymal stem cells) can regulate bone regeneration by producing secreted factors. Here, we identify KIAA1199 as a bone marrow stromal cell-secreted factor in vitro and in vivo. KIAA1199 plasma levels of patients posi...
Autores principales: | Chen, Li, Shi, Kaikai, Ditzel, Nicholas, Qiu, Weimin, Figeac, Florence, Nielsen, Louise Himmelstrup Dreyer, Tencerova, Michaela, Kowal, Justyna Magdalena, Ding, Ming, Andreasen, Christina Møller, Andersen, Thomas Levin, Kassem, Moustapha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086002/ https://www.ncbi.nlm.nih.gov/pubmed/37037828 http://dx.doi.org/10.1038/s41467-023-37651-1 |
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