Type I interferon shapes brain distribution and tropism of tick-borne flavivirus

Viral tropism within the brain and the role(s) of vertebrate immune response to neurotropic flaviviruses infection is largely understudied. We combine multimodal imaging (cm-nm scale) with single nuclei RNA-sequencing to study Langat virus in wildtype and interferon alpha/beta receptor knockout (Ifn...

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Detalles Bibliográficos
Autores principales: Chotiwan, Nunya, Rosendal, Ebba, Willekens, Stefanie M. A., Schexnaydre, Erin, Nilsson, Emma, Lindqvist, Richard, Hahn, Max, Mihai, Ionut Sebastian, Morini, Federico, Zhang, Jianguo, Ebel, Gregory D., Carlson, Lars-Anders, Henriksson, Johan, Ahlgren, Ulf, Marcellino, Daniel, Överby, Anna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086010/
https://www.ncbi.nlm.nih.gov/pubmed/37037810
http://dx.doi.org/10.1038/s41467-023-37698-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086010/
https://www.ncbi.nlm.nih.gov/pubmed/37037810
http://dx.doi.org/10.1038/s41467-023-37698-0

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