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Type I interferon shapes brain distribution and tropism of tick-borne flavivirus
Viral tropism within the brain and the role(s) of vertebrate immune response to neurotropic flaviviruses infection is largely understudied. We combine multimodal imaging (cm-nm scale) with single nuclei RNA-sequencing to study Langat virus in wildtype and interferon alpha/beta receptor knockout (Ifn...
Autores principales: | Chotiwan, Nunya, Rosendal, Ebba, Willekens, Stefanie M. A., Schexnaydre, Erin, Nilsson, Emma, Lindqvist, Richard, Hahn, Max, Mihai, Ionut Sebastian, Morini, Federico, Zhang, Jianguo, Ebel, Gregory D., Carlson, Lars-Anders, Henriksson, Johan, Ahlgren, Ulf, Marcellino, Daniel, Överby, Anna K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086010/ https://www.ncbi.nlm.nih.gov/pubmed/37037810 http://dx.doi.org/10.1038/s41467-023-37698-0 |
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