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Vascular mimicry induced by m(6)A mediated IGFL2-AS1/AR axis contributes to pazopanib resistance in clear cell renal cell carcinoma

Metastatic clear cell renal cell carcinoma (ccRCC) is a lethal sub-type of kidney cancer. Vascular mimicry (VM) has been postulated as an alternative route to supply tumors with nutrients, playing key role in tumor development. Whether VM development is linked to pazopanib efficacy, however, remains...

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Detalles Bibliográficos
Autores principales: Cheng, Bo, Xie, Mingyue, Zhou, Yong, Li, Tian, Liu, Wanting, Yu, Wenjing, Jia, Man, Yu, Shuang, Chen, Lixuan, Dai, Rongyang, Wang, Ronghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086028/
https://www.ncbi.nlm.nih.gov/pubmed/37037853
http://dx.doi.org/10.1038/s41420-023-01423-z