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Site-directed mutagenesis identified the key active site residues of 2,3-oxidosqualene cyclase HcOSC6 responsible for cucurbitacins biosynthesis in Hemsleya chinensis

Hemsleya chinensis is a Chinese traditional medicinal plant, containing cucurbitacin IIa (CuIIa) and cucurbitacin IIb (CuIIb), both of which have a wide range of pharmacological effects, including antiallergic, anti-inflammatory, and anticancer properties. However, few studies have been explored on...

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Detalles Bibliográficos
Autores principales: Li, Xia, Chen, Geng, Gao, Qing-Qing, Xiang, Chun-Fan, Yuan, Cheng-Xiao, Li, Xiao-Ning, Shu, Yan-Yu, Zhang, Guang-Hui, Liang, Yan-Li, Yang, Sheng-Chao, Zhai, Chen-Xi, Zhao, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086137/
https://www.ncbi.nlm.nih.gov/pubmed/37056503
http://dx.doi.org/10.3389/fpls.2023.1138893