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Pomegranate peel extract protects against the development of diabetic cardiomyopathy in rats by inhibiting pyroptosis and downregulating LncRNA-MALAT1

Background: Pyroptosis is an inflammatory programmed cell death accompanied by activation of inflammasomes and maturation of pro-inflammatory cytokines interleukin-1β (IL-1β) and IL-18. Pyroptosis is closely linked to the development of diabetic cardiomyopathy (DC). Pomegranate peel extract (PPE) ex...

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Detalles Bibliográficos
Autores principales: Abo-Saif, Mariam Ali, Ragab, Amany E., Ibrahim, Amera O., Abdelzaher, Othman F., Mehanyd, Ahmed B. M., Saber-Ayad, Maha, El-Feky, Ola A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086142/
https://www.ncbi.nlm.nih.gov/pubmed/37056985
http://dx.doi.org/10.3389/fphar.2023.1166653