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Induction of antigen specific intrahepatic CD8+ T cell responses by a secreted heat shock protein based gp96-Ig-PfCA malaria vaccine

INTRODUCTION: A highly efficacious and durable vaccine against malaria is an essential tool for global malaria eradication. One of the promising strategies to develop such a vaccine is to induce robust CD8+ T cell mediated immunity against malaria liver-stage parasites. METHODS: Here we describe a n...

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Detalles Bibliográficos
Autores principales: Padula, Laura, Fisher, Eva, Wijayalath, Wathsala, Patterson, Noelle B., Huang, Jun, Ganeshan, Harini, Robinson, Tanisha, Bates, François A., Hanson, Margaret A., Martin, Monica L., Rivas, Katelyn, Garcia, Denisse, Edgel, Kimberly A., Sedegah, Martha, Villasante, Eileen, Strbo, Natasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086177/
https://www.ncbi.nlm.nih.gov/pubmed/37056783
http://dx.doi.org/10.3389/fimmu.2023.1130054