Xeno-free cultured mesenchymal stromal cells release extracellular vesicles with a “therapeutic” miRNA cargo ameliorating cartilage inflammation in vitro

Rationale: Mesenchymal stromal cells (MSCs)-derived extracellular vesicles (EVs) emerged as an innovative strategy for the treatment of chronic disorders such as osteoarthritis (OA). Biological activity of EVs is generally driven by their cargo, which might be influenced by microenvironment. Therefo...

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Detalles Bibliográficos
Autores principales: Palamà, Maria Elisabetta F., Coco, Simona, Shaw, Georgina M., Reverberi, Daniele, Ghelardoni, Maddalena, Ostano, Paola, Chiorino, Giovanna, Sercia, Laura, Persano, Luana, Gagliani, Maria Cristina, Cortese, Katia, Pisignano, Dario, Murphy, Josephine Mary, Gentili, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086204/
https://www.ncbi.nlm.nih.gov/pubmed/37056573
http://dx.doi.org/10.7150/thno.77597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086204/
https://www.ncbi.nlm.nih.gov/pubmed/37056573
http://dx.doi.org/10.7150/thno.77597

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