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Neuroprotection of NAD(+) and NBP against ischemia/reperfusion brain injury is associated with restoration of sirtuin-regulated metabolic homeostasis

Background: Ischemic stroke seriously threatens human health because of high rates of morbidity, mortality and disability. This study compared the effects of nicotinamide adenine dinucleotide (NAD(+)) and butylphthalide (NBP) on in vitro and in vivo ischemic stroke models. Methods: Transient middle...

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Detalles Bibliográficos
Autores principales: Wang, Xin-Xin, Mao, Guang-Hui, Li, Qi-Qi, Tang, Jie, Zhang, Hua, Wang, Kang-Lin, Wang, Lei, Ni, Hong, Sheng, Rui, Qin, Zheng-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086243/
https://www.ncbi.nlm.nih.gov/pubmed/37056986
http://dx.doi.org/10.3389/fphar.2023.1096533