Soluble immune checkpoints as correlates for HIV persistence and T cell function in people with HIV on antiretroviral therapy

INTRODUCTION: In people with HIV (PWH) both off and on antiretroviral therapy (ART), the expression of immune checkpoint (IC) proteins is elevated on the surface of total and HIV-specific T-cells, indicating T-cell exhaustion. Soluble IC proteins and their ligands can also be detected in plasma, but...

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Detalles Bibliográficos
Autores principales: Chiu, Chris Y., Schou, Maya D., McMahon, James H., Deeks, Steven G., Fromentin, Rémi, Chomont, Nicolas, Wykes, Michelle N., Rasmussen, Thomas A., Lewin, Sharon R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086427/
https://www.ncbi.nlm.nih.gov/pubmed/37056754
http://dx.doi.org/10.3389/fimmu.2023.1123342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086427/
https://www.ncbi.nlm.nih.gov/pubmed/37056754
http://dx.doi.org/10.3389/fimmu.2023.1123342

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