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Soluble immune checkpoints as correlates for HIV persistence and T cell function in people with HIV on antiretroviral therapy

INTRODUCTION: In people with HIV (PWH) both off and on antiretroviral therapy (ART), the expression of immune checkpoint (IC) proteins is elevated on the surface of total and HIV-specific T-cells, indicating T-cell exhaustion. Soluble IC proteins and their ligands can also be detected in plasma, but...

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Detalles Bibliográficos
Autores principales:	Chiu, Chris Y., Schou, Maya D., McMahon, James H., Deeks, Steven G., Fromentin, Rémi, Chomont, Nicolas, Wykes, Michelle N., Rasmussen, Thomas A., Lewin, Sharon R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086427/ https://www.ncbi.nlm.nih.gov/pubmed/37056754 http://dx.doi.org/10.3389/fimmu.2023.1123342

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