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Effectiveness of pegfilgrastim prophylaxis in preventing febrile neutropenia during R-FC chemoimmunotherapy for chronic lymphocytic leukemia: A multicenter prospective phase II study

BACKGROUND: A chemotherapy of rituximab, fludarabine and cyclophosphamide (R-FC) has been accepted as a promising frontline chemotherapy in selected patients with chronic lymphocytic leukemia (CLL). Although R-FC regimen is a relatively dose-dense regimen and neutropenia incidence is more than 50%,...

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Detalles Bibliográficos
Autores principales: Jeon, Youngwoo, Yang, Duk-Hwan, Oh, Suk-Joong, Park, Jin-Hee, Kim, Jung-Ah, Kim, Sung-Young, Choi, Chul-Won, Lee, Won-Sik, Kim, In-Ho, Mun, Yeung-Chul, Min, Gi June, Eom, Ki-Seong, Cho, Seok-Goo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086440/
https://www.ncbi.nlm.nih.gov/pubmed/37056335
http://dx.doi.org/10.3389/fonc.2023.998014