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IL-20 subfamily cytokines impair the oesophageal epithelial barrier by diminishing filaggrin in eosinophilic oesophagitis

OBJECTIVE: Disruption of the epithelial barrier plays an essential role in developing eosinophilic oesophagitis (EoE), a disease defined by type 2 helper T cell (Th2)-mediated food-associated and aeroallergen-associated chronic inflammation. Although an increased expression of interleukin (IL)-20 su...

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Detalles Bibliográficos
Autores principales: Kaymak, Tanay, Kaya, Berna, Wuggenig, Philipp, Nuciforo, Sandro, Göldi, Andreas, Oswald, Franz, Roux, Julien, Noti, Mario, Melhem, Hassan, Hruz, Petr, Niess, Jan Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086458/
https://www.ncbi.nlm.nih.gov/pubmed/35613844
http://dx.doi.org/10.1136/gutjnl-2022-327166