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Novel TCF21(high) pericyte subpopulation promotes colorectal cancer metastasis by remodelling perivascular matrix

OBJECTIVE: Haematogenous dissemination is a prevalent route of colorectal cancer (CRC) metastasis. However, as the gatekeeper of vessels, the role of tumour pericytes (TPCs) in haematogenous metastasis remains largely unknown. Here, we aimed to investigate the heterogeneity of TPCs and their effects...

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Detalles Bibliográficos
Autores principales: Li, Xiaobo, Pan, Jinghua, Liu, Tongzheng, Yin, Wenqian, Miao, Qun, Zhao, Zhan, Gao, Yufeng, Zheng, Wei, Li, Hang, Deng, Rong, Huang, Dandan, Qiu, Shenghui, Zhang, Yiran, Qi, Qi, Deng, Lijuan, Huang, Maohua, Tang, Patrick Ming-Kuen, Cao, Yihai, Chen, Minfeng, Ye, Wencai, Zhang, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086488/
https://www.ncbi.nlm.nih.gov/pubmed/36805487
http://dx.doi.org/10.1136/gutjnl-2022-327913