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The conserved microRNA‐229 family controls low‐insulin signaling and dietary restriction induced longevity through interactions with SKN‐1/NRF2

Several microRNAs have emerged as regulators of pathways that control aging. For example, miR‐228 is required for normal lifespan and dietary restriction (DR) mediated longevity through interaction with PHA‐4 and SKN‐1 transcription factors in Caenorhabditis elegans. miR‐229,64,65, and 66, a cluster...

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Detalles Bibliográficos
Autores principales: Matai, Latika, Stathis, Thalyana, Lee, Jonathan D., Parsons, Christine, Saxena, Tanvi, Shlomchik, Kovi, Slack, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086521/
https://www.ncbi.nlm.nih.gov/pubmed/36748780
http://dx.doi.org/10.1111/acel.13785