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Transcriptional activation of Jun and Fos members of the AP‐1 complex is a conserved signature of immune aging that contributes to inflammaging

Diverse mouse strains have different health and life spans, mimicking the diversity among humans. To capture conserved aging signatures, we studied long‐lived C57BL/6J and short‐lived NZO/HILtJ mouse strains by profiling transcriptomes and epigenomes of immune cells from peripheral blood and the spl...

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Detalles Bibliográficos
Autores principales: Karakaslar, Emin Onur, Katiyar, Neerja, Hasham, Muneer, Youn, Ahrim, Sharma, Siddhartha, Chung, Cheng‐han, Marches, Radu, Korstanje, Ron, Banchereau, Jacques, Ucar, Duygu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086525/
https://www.ncbi.nlm.nih.gov/pubmed/36840360
http://dx.doi.org/10.1111/acel.13792