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Role of pulmonary epithelial arginase‐II in activation of fibroblasts and lung inflammaging

Elevated arginases including type‐I (Arg‐I) and type‐II isoenzyme (Arg‐II) are reported to play a role in aging, age‐associated organ inflammaging, and fibrosis. A role of arginase in pulmonary aging and underlying mechanisms are not explored. Our present study shows increased Arg‐II levels in aging...

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Detalles Bibliográficos
Autores principales: Zhu, Cui, Potenza, Duilio M., Yang, Yang, Ajalbert, Guillaume, Mertz, Kirsten D., von Gunten, Stephan, Ming, Xiu‐Fen, Yang, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086530/
https://www.ncbi.nlm.nih.gov/pubmed/36794355
http://dx.doi.org/10.1111/acel.13790