Homogeneity of XEN Cells Is Critical for Generation of Chemically Induced Pluripotent Stem Cells

In induced pluripotent stem cells (iPSCs), pluripotency is induced artificially by introducing the transcription factors Oct4, Sox2, Klf4, and c-Myc. When a transgene is introduced using a viral vector, the transgene may be integrated into the host genome and cause a mutation and cancer. No integrat...

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Detalles Bibliográficos
Autores principales: Jeong, Dahee, Lee, Yukyeong, Lee, Seung-Won, Ham, Seokbeom, Lee, Minseong, Choi, Na Young, Wu, Guangming, Scholer, Hans R., Ko, Kinarm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086553/
https://www.ncbi.nlm.nih.gov/pubmed/36852435
http://dx.doi.org/10.14348/molcells.2023.2127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086553/
https://www.ncbi.nlm.nih.gov/pubmed/36852435
http://dx.doi.org/10.14348/molcells.2023.2127

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