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Synthesis, molecular docking, and biological evaluation of [3,2-b]indole fused 18β-glycyrrhetinic acid derivatives against skin melanoma

Melanoma, the most serious yet uncommon type of cancer, originates in melanocytes. Risk factors include UV radiation, genetic factors, tanning lamps and beds. Here, we described the synthesis and selective anti melanoma activity of [3,2-b]indole fused 18β-glycyrrhetinic acid, a derivative of 18β-gly...

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Detalles Bibliográficos
Autores principales: Kumar, Amit, Gupta, Ragni, Rashid, Haroon, Bhat, Aalim Maqsood, Sharma, Raghu Rai, Naikoo, Shahid Hussain, Kaur, Sarabjit, Tasduq, Sheikh Abdullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086573/
https://www.ncbi.nlm.nih.gov/pubmed/37056972
http://dx.doi.org/10.1039/d2ra08023k