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Calcitriol modifies tight junctions, improves barrier function, and reduces TNF‐α‐induced barrier leak in the human lung‐derived epithelial cell culture model, 16HBE 14o‐

Using the 16HBE 14o‐ human airway epithelial cell culture model, calcitriol (Vitamin D) was shown to improve barrier function by two independent metrics – increased transepithelial electrical resistance (TER) and reduced transepithelial diffusion of (14)C‐D‐mannitol (J (m)). Both effects were concen...

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Detalles Bibliográficos
Autores principales: Rybakovsky, Elizabeth, DiGuilio, Katherine M., Valenzano, Mary Carmen, Geagan, Sophie, Pham, Kaithlyn, Harty, Ronald N., Mullin, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086678/
https://www.ncbi.nlm.nih.gov/pubmed/37038908
http://dx.doi.org/10.14814/phy2.15592