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Variability in P2X receptor composition in human taste nerves: implications for treatment of chronic cough

BACKGROUND: Antagonists to the P2X purinergic receptors on airway sensory nerves relieve refractory or unexplained chronic cough (RCC/UCC) but can evoke unwanted dysgeusias because the gustatory nerves innervating taste buds express this same family of receptors. However, the subunit composition of...

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Detalles Bibliográficos
Autores principales: High, Brigit, Jetté, Marie E., Li, Mei, Ramakrishnan, Vijay R., Clary, Matthew, Prager, Jeremy, Draf, Julia, Hummel, Thomas, Finger, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086694/
https://www.ncbi.nlm.nih.gov/pubmed/37057093
http://dx.doi.org/10.1183/23120541.00007-2023