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IFNγ blockade in capillary leak site improves tumour chemotherapy by inhibiting lactate-induced endocytosis of vascular endothelial-cadherins

IFNγ has long been recognised as a key mediator of tumour immunity and angiostasis. However, IFNγ modulation for cancer therapy is still unsuccessful due to its complex effects on various host cells. In this study, we found that treatment of Lewis lung carcinoma transplants with cisplatin often caus...

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Detalles Bibliográficos
Autores principales: Wang, Ruirui, Ni, Chen, Lou, Xiaohan, Zhang, Lijing, Wang, Linlin, Yao, Xiaohan, Duan, Xixi, Wan, Jiajia, Li, Pan, Qin, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086745/
https://www.ncbi.nlm.nih.gov/pubmed/37056922
http://dx.doi.org/10.7150/ijbs.78248