Cargando…

Serine/threonine kinase 3 promotes oxidative stress and mitochondrial damage in septic cardiomyopathy through inducing Kelch-like ECH-associated protein 1 phosphorylation and nuclear factor erythroid 2-related factor 2 degradation

Serine/threonine kinases (STK3) is a core component of the Hippo pathway and modulates oxidative stress and inflammatory responses in cardiovascular diseases. However, its potential role in septic cardiomyopathy remains undefined. STK3-mediated phosphorylation of Kelch-like ECH-associated protein 1...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Hang, Dai, Zhe, Liu, Xiaoman, Zhou, Hao, Wang, Yijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086747/
https://www.ncbi.nlm.nih.gov/pubmed/37056939
http://dx.doi.org/10.7150/ijbs.80800