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The spectrum of subclonal TP53 mutations in chronic lymphocytic leukemia: A next generation sequencing retrospective study

Chronic lymphocytic leukemia (CLL) is a hematological disorder with complex clinical and biological behavior. TP53 mutational status and cytogenetic assessment of the deletion of the corresponding locus (17p13.1) are considered the most relevant biomarkers associated with pharmaco‐predictive respons...

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Detalles Bibliográficos
Autores principales: De Luca, Giuseppa, Cerruti, Giannamaria, Lastraioli, Sonia, Conte, Romana, Ibatici, Adalberto, Di Felice, Nikki, Morabito, Fortunato, Monti, Paola, Fronza, Gilberto, Matis, Serena, Colombo, Monica, Fabris, Sonia, Ciarrocchi, Alessia, Neri, Antonino, Menichini, Paola, Ferrarini, Manlio, Nozza, Paolo, Fais, Franco, Cutrona, Giovanna, Dono, Mariella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086786/
https://www.ncbi.nlm.nih.gov/pubmed/35961859
http://dx.doi.org/10.1002/hon.3063